Comparison of two radiation dose schedules in post mastectomy carcinoma of the breast.
Indian J Med Sci
;
2000 Jul; 54(7): 278-83
Article
in English
| IMSEAR
| ID: sea-67188
ABSTRACT
In 108 histopathologically proved breast cancer patients, after surgical treatment with modified radical mastectomy, two radiation dose schedules have been compared. Radiation therapy was given on a 60Co teletherapy machine using gent pair technique for chest wall irradiation and direct fields for lymphatic drainage areas. The patients were randomly divided into two groups (Group A and Group B). 54 patients were given external radiotherapy 40 Gy/17 F/3.2 weeks and remaining 54 patients were given 45 Gy/20 F/4 weeks. Results of treatment in Group A versus Group B were as follows; chest wall failure 5/50(10%) versus 3/54 (5.6%), axillary lymphnods failure 3/50(6%) versus 4/54(7%), distant metastasis 16/50(32%) versus 15/54(28%). Radiation reactions were almost similar in both the groups. Skin reactions were most common radiation effects [45/50 (90%) in Group A and 43/54 (79.6% in Group B]. Thus no statistically significant difference in local control and efficacy of these two radiation dose schedules was observed in postmastectomy carcinoma of the breast.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Radiation Dosage
/
Breast Neoplasms
/
Aged
/
Female
/
Humans
/
Carcinoma
/
Survival Rate
/
Treatment Outcome
/
Radiotherapy, Adjuvant
Type of study:
Controlled clinical trial
/
Prognostic study
Language:
English
Journal:
Indian J Med Sci
Year:
2000
Type:
Article
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