Seroprevalence of hepatitis B virus and its co-infection with hepatitis D virus and hepatitis C virus in Iranian adult population.
Indian J Med Sci
;
2007 May; 61(5): 263-8
Article
in English
| IMSEAR
| ID: sea-68125
ABSTRACT
CONTEXT Hepatitis B virus (HBV) infection is one of the most prevalent public health problems worldwide (especially in developing countries). AIMS:
This study was carried out to determine the seroprevalence of HBV and its co-infection with hepatitis D (HDV) and C (HCV) viruses in the northeastern part of Iran. SETTING ANDDESIGN:
A population-based cross-sectional study in Iran. MATERIALS ANDMETHODS:
As many as 1,850 subjects were explored for HBsAg. Anti-HDV and anti-HCV antibodies were assessed in HBsAg-positive cases. STATISTICAL ANALYSIS USED Proportions were compared by Chi-square and Fisher's exact tests.RESULTS:
The mean age of subjects was 43.86 +/- 11.2 years. The age- and sex-standardized prevalence for HBsAg positivity was 9.7%. It was higher in males than in females (OR 1.28; 95% CI 0.9-1.7). The risk of infection in singles was significantly higher than in married cases (OR 2.13). Eight (5.8%) of HBsAg-positive cases were infected with HDV and 17 (12.3%) were positive for anti-HCV antibody.CONCLUSION:
This study demonstrates that the prevalence of HBsAg seropositivity in Golestan province of Iran is higher than the levels reported by WHO and previous studies from Iran. It is very important, especially for health providers and policy makers, to recognize the risk factors of HBV infection and its co-infection with HDV and HCV in this area and design effective preventive programs.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Hepatitis D
/
Aged
/
Female
/
Humans
/
Male
/
Hepatitis Delta Virus
/
Comorbidity
/
Seroepidemiologic Studies
/
Hepatitis B virus
/
Cross-Sectional Studies
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Sci
Year:
2007
Type:
Article
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