"Significance of serum gamma glutamyl transpeptidase in cholestatic jaundice".
Indian J Med Sci
;
1997 Aug; 51(8): 270-4
Article
in English
| IMSEAR
| ID: sea-68548
ABSTRACT
In conclusion, our study showed that serum G.G.T rises in cholestasis, and the rise is significantly higher in extraphepatic cholestasis as compared to intrahepatic cholestasis. Serum G.G.T has not shown any superiority over alkaline phosphatase in the evaluation of cholestatic liver disease. However, two considerations must caution against the use of serum G.G.T. alone for evaluation of hepatobiliary disease. The first of these is the lack of specificity for hepatobiliary disease. Serum G.G.T. activity can be elevated in some non-hepatic disorders such as acute pancreatitis, congestive cardiac failure, myocardial infarction, diabetes mellitus and alcoholism. Determination of serum G.G.T. in these patients is of no value. Second, the possibility that changes in serum G.G.T. activity results from drug administration in man.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Cholestasis, Extrahepatic
/
Female
/
Humans
/
Male
/
Cholestasis
/
Sensitivity and Specificity
/
Diagnosis, Differential
/
Alkaline Phosphatase
/
Gamma-Glutamyltransferase
/
India
Type of study:
Diagnostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Med Sci
Year:
1997
Type:
Article
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