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Human leucocytic antigens (HLA) in breast cancer.
Indian J Med Sci ; 1998 May; 52(5): 177-83
Article in English | IMSEAR | ID: sea-68763
ABSTRACT
HLA frequencies of fifty (50) female breast cancer patients were compared with 200 age matched female controls. A total of 20 HLA-A locus, 35 HLA-B locus and 8 HLA-C locus antigens were studied. The HLA-A2, A11, Aw19 and A30; HLA-B8, B14 and HLA Cw6 were found significantly higher than the controls. The HLA-A11, HLA-Aw19 and HLA-B8 were found protective whereas, HLA-A2, HLA-B14 and HLA-Cw6 were a risk for breast cancer. The prective antigens' probable involvement through immunogenic mechanism in breast cancer is emphasized in this article.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Breast Neoplasms / Aged / Female / Humans / HLA-A Antigens / HLA-B Antigens / HLA-C Antigens / Biomarkers, Tumor / Adult / HLA Antigens Language: English Journal: Indian J Med Sci Year: 1998 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Breast Neoplasms / Aged / Female / Humans / HLA-A Antigens / HLA-B Antigens / HLA-C Antigens / Biomarkers, Tumor / Adult / HLA Antigens Language: English Journal: Indian J Med Sci Year: 1998 Type: Article