Human lens epithelial layer in cortical cataract.
Indian J Ophthalmol
;
1998 Sep; 46(3): 159-62
Article
in English
| IMSEAR
| ID: sea-69759
ABSTRACT
Normal and cataractous human eye lenses were studied by morphology and protein analysis. A marked decrease in protein sulfhydryl (PSH) and nonprotein sulfhydryl (NSPH) was observed in nuclear and cortical cataractous epithelia. Moreover, decrease in PSH contents and an increase in insoluble proteins were found to be correlated only in cortical cataractous epithelium which is also accompanied by various morphological abnormalities. In nuclear cataractous epithelium, however, there was very little insolubilisation of proteins. The epithelial morphology in nuclear cataracts was almost similar to normal lens epithelium. Hence, it is assumed that the protein insolubilisation and various morphological abnormalities are characteristics of cortical cataractous epithelium. This leads us to believe that opacification in cortical cataract might initiate in the epithelial layer.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sulfhydryl Compounds
/
Cataract
/
Aged
/
Humans
/
Adult
/
Crystallins
/
Epithelium
/
Infant
/
Lens Cortex, Crystalline
/
Middle Aged
Language:
English
Journal:
Indian J Ophthalmol
Year:
1998
Type:
Article
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