Microbiological study of neonatal conjunctivitis with special reference to Chlamydia trachomatis.
Indian J Ophthalmol
;
2002 Dec; 50(4): 295-9
Article
in English
| IMSEAR
| ID: sea-70745
ABSTRACT
PURPOSE:
To study the microbial agents, chiefly Chlamydia trachomatis and other bacteria, in neonatal conjunctivitis.METHODS:
Conjunctival specimens from 70 newborns with conjunctivitis were subjected to bacterial culture and sensitivity testing, monoclonal antibody based C. trachomatis antigen detection test and species-specific Chlamydia antibody detection in the sera of babies and their mothers, by micro-immunofluorescence assay.RESULTS:
Bacteria were isolated from 35 (50%) babies; the majority (20, 57.14%) were Staphylococcus epidermidis. C. trachomatis antigen was detected in conjunctival smears of 17 (24%) babies, and 6 (35.29%) of them were positive for other bacteria. Six babies and their mothers tested positive for C. trachomatis Ig G antibodies. At follow-up after 14 weeks, 6 (35.29%) of the Chlamydia antigen-positive babies were found to have developed recurrent conjunctivitis.CONCLUSION:
C. trachomatis is responsible for almost a quarter of all cases of neonatal conjunctivitis, with recurrences in 35% of cases. Bacteria could be isolated from 50% of the patients though the exact role of Staphylococcus epidermidis, isolated from 28.65% of the neonatal conjunctivitis cases, remains unclear.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ophthalmic Solutions
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Chlamydia Infections
/
Microbial Sensitivity Tests
/
Chlamydia trachomatis
/
Ophthalmia Neonatorum
/
Risk Factors
Type of study:
Etiology study
/
Risk factors
Language:
English
Journal:
Indian J Ophthalmol
Year:
2002
Type:
Article
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