Familial unilateral Brown syndrome.
Indian J Ophthalmol
;
2008 Sep-Oct; 56(5): 430-4
Article
in English
| IMSEAR
| ID: sea-70796
ABSTRACT
We present a two-generation family with Brown syndrome. The proband was a six and a half-year-old female who presented with a history of failure of dextro-elevation of her left eye. A full ophthalmic evaluation was consistent with a left Brown syndrome. Family history revealed that her mother was operated on as a child for left Brown syndrome and examination of her four and a half-year-old sibling showed similar affection in the left eye. Autosomal dominant inheritance has been postulated in this condition. To our knowledge this is the first report of three members of a two-generation family with left-sided Brown syndrome. Genetic counseling of Brown syndrome cases is advised; nevertheless, identification of the responsible gene should shed more light on its genetics.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pedigree
/
Phenotype
/
Female
/
Humans
/
Male
/
Vision, Binocular
/
Nuclear Family
/
Ocular Motility Disorders
/
Child
/
Follow-Up Studies
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Indian J Ophthalmol
Year:
2008
Type:
Article
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