Economic impact of a rotavirus vaccine in Brazil.
J Health Popul Nutr
;
2008 Dec; 26(4): 388-96
Article
in English
| IMSEAR
| ID: sea-713
ABSTRACT
The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccination programme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$ 7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Rotavirus Infections
/
Brazil
/
Female
/
Humans
/
Male
/
Child, Preschool
/
Cohort Studies
/
Cost-Benefit Analysis
/
Rotavirus
/
Rotavirus Vaccines
Type of study:
Etiology study
/
Health economic evaluation
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
J Health Popul Nutr
Journal subject:
Gastroenterology
/
Nutritional Sciences
/
Public Health
Year:
2008
Type:
Article
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