Visual outcomes of pan-retinal photocoagulation in diabetic retinopathy at one-year follow-up and associated risk factors.
Indian J Ophthalmol
;
2005 Jun; 53(2): 93-9
Article
in English
| IMSEAR
| ID: sea-72567
ABSTRACT
PURPOSE:
To assess the visual outcomes at one-year follow-up after pan-retinal photocoagulation (PRP) in type 2 diabetes mellitus subjects with proliferative diabetic retinopathy (PDR) and associated risk factors. MATERIALS ANDMETHODS:
A retrospective study, using data from medical records of 5000 Type 2 diabetic patients who underwent a retinal examination between 1995 and 1999 at a diabetic centre. Ocular, clinical and biochemical parameters were assessed at baseline and at one-year follow-up after PRP. Diabetic retinopathy (DR) was documented by colour photography and PRP was performed according to the ETDRS criteria.RESULTS:
PRP was done in 413 eyes, of which 261 eyes of 160 subjects were eligible for the study. One hundred and forty eyes (73%) of 191 eyes with good visual acuity (6/9) at baseline maintained the same vision at one-year follow-up. Of the 53 eyes with visual acuity of 6/12-6/36 at baseline, 58.5% (31 eyes) maintained same vision and 18.9% (10 eyes) improved their vision at one-year follow-up. Of the 17 eyes with visual acuity < or =6/60 at baseline, 12 maintained the same vision and the remaining 5 improved their vision. The causes of visual loss included vitreous haemorrhage in 20 subjects (31.7%), progression of cataract in 19 (30%), chronic macular oedema in 15 (23.8%), pre-retinal haemorrhage in the macula in 6 (9.5%) and pre-retinal fibrosis in the macula in 3 (4.7%) subjects. On multiple logistic regression analysis, diastolic blood pressure (P =0.03), duration of diabetes (P =0.006), fasting blood glucose (P =0.02) and nephropathy (P =0.01) were associated with decreased vision after PRP. Glycated haemoglobin (HbA1c) (P < 0.001), serum creatinine (P =0.03), HDL cholesterol (P =0.05), diabetic neuropathy (P < 0.001), hypertension (P =0.01) and diabetic nephropathy (P < 0.001) showed a significant association with PDR.CONCLUSION:
Visual acuity at baseline, the duration of diabetes and proteinuria played a significant role in determining the post-PRP visual acuity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Time Factors
/
Blood Glucose
/
Blood Pressure
/
Female
/
Humans
/
Male
/
Visual Acuity
/
Retrospective Studies
/
Risk Factors
/
Follow-Up Studies
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Indian J Ophthalmol
Year:
2005
Type:
Article
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