BCG, tuberculin skin-test results and asthma prevalence in school children in North London.
Indian Pediatr
;
2002 Mar; 39(3): 254-8
Article
in English
| IMSEAR
| ID: sea-7285
ABSTRACT
OBJECTIVE:
To test whether there is any relationship between asthma prevalence and BCG immunization or tuberculin skin text reaction.DESIGN:
Cross-sectional survey.SETTING:
Secondary school in Haringey, North London, U.K.SUBJECTS:
780 children aged 11-18 years (median 13.35 years).INTERVENTIONS:
Administration of tuberculin skin text and questionnaire. MAIN OUTCOMEMEASURES:
Diagnosis of asthma, presence of nocturnal cough, exercise-induced wheeze or wheeze with viral respiratory infections; diameter of induration with tuberculin skin text; history of BCG immunization.RESULTS:
57 of 629 children (8.5%) had a significantly positive Mantoux reaction (>or=15 millimeters of induration). Children with and without a history of BCG immunization did not differ significantly in prevalence of asthma diagnosis (11.8% vs 14.1%, p > 0.6), exercise-induced wheeze (16.9% vs 21.2%, p>0.4), viral induced wheeze (15.4% vs 7%, p>0.6) or nocturnal cough (32.3% vs 32.7%, p> 0.6). We also found no significant correlation of the prevalence of asthma diagnosis or symptoms with diameter of Mantoux test reaction.CONCLUSION:
There is no evidence of an effect of BCG immunization or tuberculin reactivity on the incidence of asthma in secondary school children in Haringey, North London and the exposure to tuberculosis is high in these children.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Asthma
/
Female
/
Humans
/
Male
/
Tuberculin Test
/
BCG Vaccine
/
Child
/
Cross-Sectional Studies
/
Surveys and Questionnaires
/
Adolescent
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Country/Region as subject:
Europa
Language:
English
Journal:
Indian Pediatr
Year:
2002
Type:
Article
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