Serological evidence for active Epstein-Barr virus infection in multifocal choroiditis.

Bhende, P S; Biswas, J; Madhavan, H N

Bhende, P S; Biswas, J; Madhavan, H N.

Indian J Pathol Microbiol ; 1997 Apr; 40(2): 129-31

Article in English | IMSEAR | ID: sea-73583

ABSTRACT

ABSTRACT

Six patients, consisting of 4 males and 2 females with mean average age fo 29.20 years, with variable picture of multifocal choroiditis were serologically investigated for their association with Epstein-Barr Virus (EBV) infection. IgG and IgM antibodies to EBV-Virus Capsid Antigen (VCA) were assayed by immunoperoxidase method on EBV infected lymphoblast cells (P3HR-1 Burkitt's lymphoma cell line). In these patients definite serological evidence of EBV infection with high titres of IgG and IgM antibodies to EBV-VCA was demonstrated suggestive of active continuing or persisting EBV infection.

Subject(s)

Adult; Antibodies, Viral/analysis; Antigens, Viral/immunology; Capsid Proteins; Cells, Cultured; Female; Herpesviridae Infections/blood; Herpesvirus 4, Human/immunology; Humans; Immunoglobulin G/analysis; Immunoglobulin M/analysis; Male; Middle Aged

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Female / Humans / Male / Immunoglobulin G / Immunoglobulin M / Cells, Cultured / Herpesvirus 4, Human / Herpesviridae Infections / Adult / Capsid Proteins Language: English Journal: Indian J Pathol Microbiol Year: 1997 Type: Article

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