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Cytological grading of breast neoplasia and its correlation with histological grading.
Indian J Pathol Microbiol ; 2006 Apr; 49(2): 208-13
Article in English | IMSEAR | ID: sea-73587
ABSTRACT
Cytological grading of breast cancer is not well established despite histological grading having gained a strong foothold. In our study we have analyzed 50 cases of breast carcinoma which included invasive ductal carcinoma, invasive lobular carcinoma, mucinous carcinoma, stromal sarcoma, apocrine carcinoma, papillary carcinoma. Papanicolaou smears were graded according to established Hunt's, Simplified Black and Modified Black grading systems. They were then compared with the Scarff Bloom Richardson grading system. Simplified Black grading system has been recommended for cytological grading of breast neoplasia because of its lucidity and its reproducibility. Cytological grading of breast neoplasia is important for neo adjuvant chemotherapy and also for predicting the prognosis of the patient on FNAC alone. Incorporation of other parameters like apoptosis and bcl-2 is also recommended.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Breast Neoplasms / Female / Humans / Retrospective Studies / Histological Techniques / Adult / Cytodiagnosis / Middle Aged Type of study: Observational study Language: English Journal: Indian J Pathol Microbiol Year: 2006 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Breast Neoplasms / Female / Humans / Retrospective Studies / Histological Techniques / Adult / Cytodiagnosis / Middle Aged Type of study: Observational study Language: English Journal: Indian J Pathol Microbiol Year: 2006 Type: Article