Cell adherence--a determinant of virulence in Yersinia enterocolitica.
Indian J Pathol Microbiol
;
2006 Jan; 49(1): 49-50
Article
in English
| IMSEAR
| ID: sea-73641
ABSTRACT
The adherence of pathogenic bacteria to eukaryotic cells plays a central role in their ability to colonize the mucosal epithelial surfaces. The adherence by Y. enterocolitica to the mucosal surface of the gut is the initiating event leading to penetration of mucosa. Adhesion of 10 probable pathogenic and one non-pathogenic isolate was studied using ileum and colon epithelial cells of mouse for 90 minutes. Adhesion study revealed that isolates of Y. enterocolitica had a good adhesive property while non pathogenic showed negligible adherence. All isolates showed better adherence to colon epithelial cells. The organism continued to be excreted in faeces up to 8-10 days after oral feeding. Adhesion positive isolates were found to be virulent when tested in mice for diarrhoea and death. Adhesion was found to be thermoregulated.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Virulence
/
Yersinia enterocolitica
/
Yersinia Infections
/
Bacterial Adhesion
/
Survival Analysis
/
Cells, Cultured
/
Colon
/
Diarrhea
/
Epithelial Cells
/
Feces
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2006
Type:
Article
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