Neuropathology of schizophrenia--a review.
Indian J Pathol Microbiol
;
2003 Apr; 46(2): 165-9
Article
in English
| IMSEAR
| ID: sea-73708
ABSTRACT
Despite clinical evidence of brain dysfunction in schizophrenia, little progress was made for most of the last century in determining its organic parameters. Neuropathology, over the past few decades, has made a substantial contribution to the understanding of cellular and molecular mechanisms of schizophrenia. During the last 10-15 years the concept of schizophrenia as a 'functional' psychosis has changed to the current paradigm of schizophrenia as a neurodevelopmental disorder. Much still has to be unravelled and learnt. This review gives a brief account of the relevant neuroanatomy, viral hypotheses of schizophrenia etiology, pathologic findings reported, concept of neurodevelopmental model and avenues for the future.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Schizophrenia
/
Brain
/
Humans
/
Prefrontal Cortex
/
Hippocampus
/
Animals
/
Models, Neurological
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2003
Type:
Article
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