Quick score of hormone receptor status of breast carcinoma: correlation with the other clinicopathological prognostic parameters.
Indian J Pathol Microbiol
;
2009 Apr-Jun; 52(2): 159-63
Article
in English
| IMSEAR
| ID: sea-73827
ABSTRACT
BACKGROUND:
Immunohistochemical assessment of the hormone receptor status of breast carcinoma is a routine investigation. However, there is no worldwide consensus on the scoring system. The Quick Score is claimed to be a reliable scoring system, which assesses both the proportion of stained cells and the intensity of staining.AIMS:
To assess the value of Quick Score in terms of accepted clinicopathological parameters and to document the prevalence of hormone receptor-positive breast carcinomas in the study sample. MATERIALS ANDMETHODS:
Clinicopathological parameters of 151 breast cancers were compared with the Quick Scores for estrogen receptor (ER) and progesterone receptor (PR) status. RESULTS ANDCONCLUSIONS:
The Quick Score for ER was 0 in 54.3% (82/151) and for PR was 0 in 51.7% (75/145), indicating no hormone receptor expression in the majority. The Nottingham grade and the mitotic count had a significant inverse relationship with the Quick Score for hormone receptor status. The Nottingham Prognostic Index (NPI) also had an inverse relationship with the hormone receptor status.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2009
Type:
Article
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