Study of anticardiolipin antibodies in repeated abortions--an institutional experience.
Indian J Pathol Microbiol
;
2001 Apr; 44(2): 117-21
Article
in English
| IMSEAR
| ID: sea-73905
ABSTRACT
A cohort of 178 pregnant women with a history of first or second trimester abortions (2 or more) were the base of present study. In all, other causes of abortion were ruled out except for anti-phospholipid syndrome. Anti-Cardiolipin antibody (ACA) (IgG & IgM) was estimated in the sera samples of all women. Out of 178 women, any one or both immunoglobulins were above the cut off range (> 15.0 units) in 47 (26.4%) while both immunoglobulins were normal in 131 (73.59%) women. Both immunoglobulins were present in only 0.5% women. ACA-IgG alone was present in 11.79% while ACA-IgM alone was present in 14.04% women. We observe from present study that ACA is a major cause of recurrent fetal loss & many pregnancies can be saved if diagnosed & treated adequately.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Immunoglobulin G
/
Immunoglobulin M
/
Pregnancy
/
Abortion, Habitual
/
Cohort Studies
/
Adolescent
/
Antiphospholipid Syndrome
/
Antibodies, Anticardiolipin
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Risk factors
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2001
Type:
Article
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