Platelet large cell ratio in the differential diagnosis of abnormal platelet counts.
Indian J Pathol Microbiol
;
2004 Apr; 47(2): 202-5
Article
in English
| IMSEAR
| ID: sea-74267
ABSTRACT
Platelet volume indices, estimated by automated blood cell analyzers, are useful in the diagnosis of various conditions with abnormal platelet counts. Platelet count (PLT), Platelet large cell ratio (P-LCR), Platelet distribution width (PDW) and mean platelet volume (MPV) were studied in 779 patients with normal platelet counts, 74 patients with high platelet counts and 41 cases with low platelet counts. P-LCR was significantly decreased in patients with thrombocytosis than in normal while it was increased in thrombocytopenia. In patients with high counts, P-LCR was significantly decreased in reactive thrombocytosis than neoplastic thrombocytosis. P-LCR was increased in destructive thrombocytopenia than those with hypoproliferative thrombocytopenia though it was not statistically significant. P-LCR was inversely related to platelet count and directly related to PDW and MPV. Platelet large cell ratio if properly utilised can be a good aid in the differential diagnosis of conditions associated with abnormal platelet counts.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Platelet Count
/
Thrombocytopenia
/
Thrombocytosis
/
Blood Platelets
/
Humans
/
Cell Size
/
Diagnosis, Differential
/
Neoplasms
Type of study:
Diagnostic study
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2004
Type:
Article
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