Embryonal rhabdomyosarcoma of the chest wall: a case report and review of the literature.
Indian J Pathol Microbiol
;
2008 Apr-Jun; 51(2): 274-6
Article
in English
| IMSEAR
| ID: sea-74855
ABSTRACT
Embryonal rhabdomyosarcoma is a soft-tissue sarcoma which has a predilection for the head and neck area, genitourinary tract and the extremities. We report a rare case of embryonal rhabdomyosarcoma of the chest wall in an 8-year-old girl, presenting as a destructive tumor in the rib and clinically and radiologically mimicking Ewing's sarcoma. Histopathological examination showed a small round cell tumor. Immunohistochemically, the positivity for muscle markers desmin and myogenin in the tumor cells proved to be useful for making a definitive diagnosis of embryonal rhabdomyosarcoma. Cytogenetic analysis revealed a high level of aneuploidy in the tumor cells, with double-minutes and additional chromosomal structural aberrations. The patient is responding well to chemotherapy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Sarcoma, Ewing
/
Thoracic Neoplasms
/
Female
/
Humans
/
Child
/
Rhabdomyosarcoma, Embryonal
/
Thoracic Wall
/
Diagnosis, Differential
/
Aneuploidy
Type of study:
Diagnostic study
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2008
Type:
Article
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