AgNOR counts are not altered in alcoholic cirrhosis.
Indian J Pathol Microbiol
;
2003 Apr; 46(2): 170-2
Article
in English
| IMSEAR
| ID: sea-75409
ABSTRACT
One hundred and two liver biopsy specimens were stained for Argyrophilic nucleolar organizer regions and associated proteins to assess its utility in differentiating normal, cirrhotic and neoplastic liver tissue. A statistically significant (p < 0.001) difference was observed between mean AgNOR counts of normal (1.53 +/- 0.4), post-hepatitic cirrhosis (3.65 +/- 0.53) and hepatocellular carcinoma (7.94 +/- 1.18). In contrast the mean AgNOR count of biopsies with alcoholic cirrhosis (1.57 +/- 0.06) was significantly less (p < 0.001) than post-hepatitic cirrhosis and was similar to that of normal liver tissue. It is concluded that AgNORs can act as a good adjuvant to histology in diagnosing liver diseases especially in differentiating post-hepatitic and alcoholic cirrhosis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Silver
/
Staining and Labeling
/
Humans
/
Case-Control Studies
/
Carcinoma, Hepatocellular
/
Hepatitis
/
Liver
/
Liver Cirrhosis
/
Liver Cirrhosis, Alcoholic
/
Liver Neoplasms
Type of study:
Observational study
/
Risk factors
Language:
English
Journal:
Indian J Pathol Microbiol
Year:
2003
Type:
Article
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