Efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.
Indian J Pediatr
;
2005 Nov; 72(11): 935-8
Article
in English
| IMSEAR
| ID: sea-78313
ABSTRACT
OBJECTIVE:
A double-blind randomized controlled-trial was done to evaluate the efficacy of tyndalized Lactobacillus acidophilus in acute diarrhea.METHODS:
All children from 6 months to 12 years with acute diarrhea were included. Lactobacillus acidophilus/placebo was given to the children for 3 days with ORS and feeds. Intake-output was recorded 4 hourly. Of the 98 children, 48 received lactobacillus and 50 the placebo.RESULTS:
ORS consumed, frequency of stools, duration of diarrhea, time for rehydration, hospital stay, weight gain and IVF needed were comparable in the two study groups. There were 4 treatment failures in the lactobacillus group and none in the placebo group (OR 0.92, 95%CI 0.84-0.99). In the rotaviral diarrhea and in those who had diarrhea of less then 60 hours the difference did not reach statistical significance.CONCLUSION:
There is no significant benefit of tyndalized Lactobacillus acidophilus in acute diarrhea.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Child
/
Child, Preschool
/
Double-Blind Method
/
Acute Disease
/
Combined Modality Therapy
/
Probiotics
/
Diarrhea
/
Fluid Therapy
/
Infant
Type of study:
Controlled clinical trial
Language:
English
Journal:
Indian J Pediatr
Year:
2005
Type:
Article
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