Qualitative evaluation of tuberculin test responses in childhood tuberculosis.
Indian J Pediatr
;
2007 Jul; 74(7): 641-4
Article
in English
| IMSEAR
| ID: sea-78476
ABSTRACT
OBJECTIVE:
To study if different forms of clinical presentation of tuberculosis in children are associated with a different type of tuberculin reaction.METHODS:
This cross sectional study, describing Tuberculin skin testing (TST) responses in 268 children (134 cases and 134 controls) less than 12 yr of age was carried out over a period of 18 months at JIPMER, a tertiary care referral hospital in Pondicherry, India. The qualitative and quantitative TST responses in various clinical forms of Tuberculosis were analysed.RESULTS:
Koch's and Listeria variants were more common in children with TB Lymphadenitis and Pulmonary TB respectively. 10% of the study children with TB meningitis were tuberculin negative.CONCLUSION:
Qualitative TST responses are non-homogeneous among the various clinical types of childhood tuberculosis. They are not a correlate of protective immunity with little or no prognostic significance.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculosis
/
Humans
/
Tuberculin Test
/
BCG Vaccine
/
Child
/
Child, Preschool
/
Infant
Type of study:
Observational study
/
Prognostic study
/
Qualitative research
Language:
English
Journal:
Indian J Pediatr
Year:
2007
Type:
Article
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