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Qualitative evaluation of tuberculin test responses in childhood tuberculosis.
Indian J Pediatr ; 2007 Jul; 74(7): 641-4
Article in English | IMSEAR | ID: sea-78476
ABSTRACT

OBJECTIVE:

To study if different forms of clinical presentation of tuberculosis in children are associated with a different type of tuberculin reaction.

METHODS:

This cross sectional study, describing Tuberculin skin testing (TST) responses in 268 children (134 cases and 134 controls) less than 12 yr of age was carried out over a period of 18 months at JIPMER, a tertiary care referral hospital in Pondicherry, India. The qualitative and quantitative TST responses in various clinical forms of Tuberculosis were analysed.

RESULTS:

Koch's and Listeria variants were more common in children with TB Lymphadenitis and Pulmonary TB respectively. 10% of the study children with TB meningitis were tuberculin negative.

CONCLUSION:

Qualitative TST responses are non-homogeneous among the various clinical types of childhood tuberculosis. They are not a correlate of protective immunity with little or no prognostic significance.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Tuberculosis / Humans / Tuberculin Test / BCG Vaccine / Child / Child, Preschool / Infant Type of study: Observational study / Prognostic study / Qualitative research Language: English Journal: Indian J Pediatr Year: 2007 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Tuberculosis / Humans / Tuberculin Test / BCG Vaccine / Child / Child, Preschool / Infant Type of study: Observational study / Prognostic study / Qualitative research Language: English Journal: Indian J Pediatr Year: 2007 Type: Article