Nasopharyngeal carriage of Haemophilus influenzae.
Indian J Pediatr
;
2002 Sep; 69(9): 775-7
Article
in English
| IMSEAR
| ID: sea-78624
ABSTRACT
OBJECTIVE:
Nasopharyngeal colonization of Haemophilus influenzae (H. influenzae) in young children may be important in developing countries.METHOD:
In this study, we screened school going children for carriage of H. influenzae. A total of 44 H. influenzae isolates out of a collection of 162 were characterized for biotypes, capsular serotypes and antibiotic resistance.RESULTS:
A significant proportion of H. influenzae (25/44) isolates were serotype b. High antibiotic resistance was observed against commonly administered antibiotics like ampicillin (79%), chloramphenicol (20%), trimethoprim sulfamethoxazole (84%) and erythromycin (95%). Comparison of antibiotic resistance profile of nasopharyngeal isolates was observed to be correlated with those of H. influenzae from disease.CONCLUSION:
Multidrug resistant nasopharyngeal H. influenzae in young healthy children may act as reservoir. Monitoring of antibiotic resistance among nasopharyngeal H. influenzae as a surrogate for invasive H. influenzae seems an attractive option.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Carrier State
/
Microbial Sensitivity Tests
/
Child
/
Child, Preschool
/
Mass Screening
/
Nasopharynx
/
Haemophilus influenzae
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
/
Risk factors
/
Screening study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Pediatr
Year:
2002
Type:
Article
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