Serodiagnosis of subacute sclerosing panencephalitis by enzyme linked immunosorbent assay.
Indian J Pediatr
;
1993 Jan-Feb; 60(1): 37-41
Article
in English
| IMSEAR
| ID: sea-78948
ABSTRACT
Thirty three young patients (23 males and 10 females), between 3-20 years of age, with a clinical suspicion of subacute sclerosing panencephalitis (SSPE) were evaluated over a period of 4 years. A past history of measles was obtained in 42.4% of the cases. One child was immunised against measles. Measles specific antibodies (IgG) were demonstrated in the cerebrospinal fluid (CSF) from 30 (90.9%) of the 33 patients by ELISA. In the remaining three cases the antibodies were detected only in the serum. Serodiagnosis of SSPE by ELISA had a sensitivity of 100%, a specificity of 93.3% and a positive predictive value of 100%.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Subacute Sclerosing Panencephalitis
/
Female
/
Humans
/
Male
/
Enzyme-Linked Immunosorbent Assay
/
Serologic Tests
/
Child
/
Child, Preschool
/
Sensitivity and Specificity
/
Adolescent
Type of study:
Diagnostic study
/
Prognostic study
Language:
English
Journal:
Indian J Pediatr
Year:
1993
Type:
Article
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