Fetal hydantoin syndrome with rheumatic valvular heart disease.

Godbole, K G; Gambhir, P S; Deshpande, A S; Kurlekar, S U; Phadke, M A

Godbole, K G; Gambhir, P S; Deshpande, A S; Kurlekar, S U; Phadke, M A.

Indian J Pediatr ; 1999 Mar-Apr; 66(2): 290-3

Article in English | IMSEAR | ID: sea-78998

ABSTRACT

ABSTRACT

Research has shown that anticonvulsants are teratogens and pose a risk for fetal malformations. Though Fetal Hydantoin Syndrome (FHS) was first reported by Langhman and others, wide phenotypic variability of this syndrome has lead many clinicians to question its very existence. We report a twelve year old girl with FHS with rheumatic valvular heart disease.

Subject(s)

Abnormalities, Drug-Induced/etiology; Anticonvulsants/adverse effects; Child; Female; Hand Deformities, Congenital/chemically induced; Humans; Intellectual Disability/chemically induced; Nails, Malformed/chemically induced; Phenytoin/adverse effects; Rheumatic Heart Disease/complications; Syndrome

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Phenytoin / Rheumatic Heart Disease / Syndrome / Abnormalities, Drug-Induced / Female / Humans / Hand Deformities, Congenital / Child / Intellectual Disability / Anticonvulsants Language: English Journal: Indian J Pediatr Year: 1999 Type: Article

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