Chemotherapy related fatal neurotoxicity during induction in acute lymphoblastic leukemia.
Indian J Pediatr
;
2002 Feb; 69(2): 185-7
Article
in English
| IMSEAR
| ID: sea-79057
ABSTRACT
Neurotoxicity is a common complication during cancer chemotherapy. It is estimated that 3-10% of children with acute lymphoblastic leukemia (ALL) experience acute, transient neurotoxicity during induction chemotherapy. Fatal acute neurotoxicity is rarely encountered. Neurological evaluation of children with ALL at diagnosis and during treatment is of value in order to diagnose neurological complications early so that appropriate intervention can be adopted. This communication describes the profile of two children with unexpected, acute fatal neurologic toxicity during induction chemotherapy for ALL.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Asparaginase
/
Vincristine
/
Humans
/
Male
/
Dexamethasone
/
Antineoplastic Combined Chemotherapy Protocols
/
Child
/
Child, Preschool
/
Methotrexate
/
Fatal Outcome
Language:
English
Journal:
Indian J Pediatr
Year:
2002
Type:
Article
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