'Thinfat' phenotype in newborns.
Indian J Pediatr
;
2009 Apr; 76(4): 369-73
Article
in English
| IMSEAR
| ID: sea-79916
ABSTRACT
OBJECTIVE:
The objectives of the study was to know whether the 'thinfat' phenotype exists in newborns, in Central Karnataka and to correlate various factors that contribute to this peculiar phenotype, with emphasis on genetic and maternal environmental factors.METHODS:
For 1000 consecutive singleton term newborns, weight, length, head, mid arm, abdominal circumferences, biceps and subscapular skinfolds were measured at birth and compared with measurements of white Caucasian babies born in Southampton UK and Mysore babies at birth.RESULTS:
The Davangere babies were significantly smaller in all measurements at birth (p < 0.001) compared to Southampton babies. The deficit varied according to the measurements; It was greatest for birth weight (-1.6 SD, CI -3.0, -0.2), mid arm circumference (-2.0 SD, CI -3.3, -0.8), head circumference (-1.8 SD, CI -3.1, -0.5) and least for length (-0.4 SD, CI -1.9, 1.1) and subscapular skin fold (-0.3 SD, CI -0.25, -0.12). Predictors of skinfold thickness were maternal body mass index (p < 0.05), maternal mid arm circumference (p < 0.001) and consanguinity (p < 0.05).CONCLUSION:
Despite being small, truncal adiposity was present in Davangere neonates confirming the 'thinfat' phenotype. The role of consanguinity in other words, the role of genes, is important in determining this 'thinfat' phenotype in newborns.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenotype
/
Skinfold Thickness
/
Birth Weight
/
Humans
/
Infant, Newborn
/
Body Mass Index
/
Anthropometry
/
Maternal Age
/
Young Adult
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pediatr
Year:
2009
Type:
Article
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