Tuberculin sensitivity among children vaccinated with BCG under universal immunization programme.
Indian J Pediatr
;
2004 Dec; 71(12): 1063-8
Article
in English
| IMSEAR
| ID: sea-80838
ABSTRACT
A tuberculin survey was conducted among 45988 children with BCG scar and 54227 children without BCG scar between 1-9 years of age and residing in selected rural areas of three defined zones of India. About 45-60% of the BCG-vaccinated children elicited reactions < 5 mm in size and about 70-80% had reactions < 10 mm. Therefore, in the majority of children (showing tuberculin reaction of < 10 mm), BCG-induced tuberculin sensitivity does not interfere with interpretation of tuberculin test. The study also revealed that a proportion of reactions among BCG vaccinated children in 5-9 mm, 10-14 mm and 15-19 mm range may be attributable to BCG vaccination. Therefore, reactions between 10-14 mm and especially 15-19 mm among the vaccinated children must be interpreted carefully. However, 19 mm was observed as the upper limit for BCG induced tuberculin sensitivity and all reactions >- 20 mm in size may be considered to be due to infection with tubercle bacilli, irrespective of the BCG vaccination status.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculin
/
Tuberculosis
/
Humans
/
Tuberculin Test
/
BCG Vaccine
/
Child
/
Child, Preschool
/
Cicatrix
/
Immunization Programs
/
Drug Hypersensitivity
Language:
English
Journal:
Indian J Pediatr
Year:
2004
Type:
Article
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