Recurrent acute transverse myelopathy: association with antiphospholipid antibody syndrome.
Indian J Pediatr
;
2004 Jun; 71(6): 559-61
Article
in English
| IMSEAR
| ID: sea-81147
ABSTRACT
A seven-year-old boy presented with a second episode of acute transverse myelopathy. The first episode had responded dramatically to methylprednisolone. The manifestations of the second episode did not respond to methylprednisolone or IVIG. He showed persistently raised levels of antiphospholipid antibodies in the serum. Primary conditions like collagen vascular diseases, malignancy, exposure to drugs and HIV infection, which are known to be associated with the raised titers of these antibodies were ruled out clinically and by investigations. Recurrent transverse myelopathy is a rare event in childhood and reports of its association with Antiphospholipid Antibody Syndrome (APLAS) are scanty. The etiological role for these antibodies remains to be established. However, once the diagnosis is established, it may be prudent to treat the condition with agents and procedures to bring about a decrease in their titers. Long-term therapy to prevent thromboembolic complications of APLAS may also be instituted.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Humans
/
Male
/
Methylprednisolone
/
Magnetic Resonance Imaging
/
Child
/
Acute Disease
/
Antiphospholipid Syndrome
/
Anti-Inflammatory Agents
/
Myelitis, Transverse
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pediatr
Year:
2004
Type:
Article
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