Effect of gender, birth weight and gestational age on serum 17-hydroxyprogesterone concentration and distribution among neonates in Saudi Arabia.
Indian J Pediatr
;
1995 Sep-Oct; 62(5): 605-9
Article
in English
| IMSEAR
| ID: sea-82077
ABSTRACT
Blood samples from 813 newborns were spotted on to filter paper and the 17-hydroxyprogesterone concentration was measured using the Delfia (R) fluorometric immunoassay. The median, mean, and standard deviation (SD) for the total population were 20, 21 and (11) nmol/L respectively. Males had significantly higher levels than females with median, mean and (SD) of 22, 22 and (12) nmol/L. Similarly, low birth weight babies were found to have significantly higher levels than normal birth weight babies with median, mean and (SD) of 21, 24 (12) nmol/L. Preterm babies were also found to have significantly higher levels than full term babies, with median, mean and (SD) of 25, 29 (16) nmol/L. As experienced elsewhere, those factors should be taken into consideration when considering a cut-off point in any neonatal screening program for congenital adrenal hyperplasia.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Reference Values
/
Saudi Arabia
/
Birth Weight
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Gestational Age
/
Neonatal Screening
/
Adrenal Hyperplasia, Congenital
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Pediatr
Year:
1995
Type:
Article
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