Paradoxical response to antitubercular drugs.

Kumar, S; Puri, V; Mehndiratta, M M; Gupta, S; Bhutani, A; Sharma, C

Kumar, S; Puri, V; Mehndiratta, M M; Gupta, S; Bhutani, A; Sharma, C.

Indian J Pediatr ; 1995 Nov-Dec; 62(6): 695-701

Article in English | IMSEAR | ID: sea-82130

ABSTRACT

ABSTRACT

Seven patients with paradoxical response to antitubercular drugs are reported. In three cases of intracranial tuberculomas, newer lesions appeared and in two cases preexisting tuberculomas enlarged. In two cases of tubercular meningitis, multiple tuberculomas appeared. All these cases exhibited newer symptoms and CT/MBI revealed the paradoxical response to antitubercular drugs. All responded to continued conservative therapy, with addition of pyrazinamide.

Subject(s)

Adolescent; Antitubercular Agents/adverse effects; Brain Diseases/etiology; Child; Female; Humans; Magnetic Resonance Imaging; Male; Tomography, X-Ray Computed; Tuberculoma/etiology; Tuberculosis, Meningeal/drug therapy

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Tuberculoma / Tuberculosis, Meningeal / Brain Diseases / Female / Humans / Male / Magnetic Resonance Imaging / Tomography, X-Ray Computed / Child / Adolescent Language: English Journal: Indian J Pediatr Year: 1995 Type: Article

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