Hematological manifestations of congenital cytomegalovirus infection.
Indian J Pediatr
;
1995 Jul-Aug; 62(4): 473-7
Article
in English
| IMSEAR
| ID: sea-82750
ABSTRACT
Nine infants suffering from congenital cytomegalovirus infection were studied for clinical features with special reference to hematological manifestations. The mean age of appearance of first clinical symptom of disease was 14 days and mean age at presentation was 58 days. Significant pallor, thrombocytopenia and evidence of hemolysis were present in 8 (89%), 4 (44%) and 4 (44%) patients respectively out of three bone marrow examination performed, paucity of erythroid and megakaryocytic cells were seen in two. The other clinical features included hepatomegaly in a (100%) splenomegaly in 6 (66%) each, petachial rash in 5 (55%), Hepatitis in 4 (44%) optic atrophy and corneal opacities in one patient each. Two patients died. Remaining patients showed symptomatic improvement without specific therapy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Infant, Newborn
/
Survival Analysis
/
Cytomegalovirus Infections
/
Hematologic Diseases
/
India
Type of study:
Prognostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Pediatr
Year:
1995
Type:
Article
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