Endocrinological parameters in experimental unilateral undescended testis.
Indian J Pediatr
;
1999 Mar-Apr; 66(2): 193-6
Article
in English
| IMSEAR
| ID: sea-82870
ABSTRACT
It is a common clinical practice to estimate FSH, LH and testosterone levels in patients with unilateral undescended testis (U/L UDT) as a prognostic pointer to fertility potential. Is this practice correct? To ascertain this aspect, new born rats were operated to create experimental U/L UDT by gubernaculectomy and anchoring the gubernaculum to anterior abdominal wall. Fertility and hormone levels were evaluated later in adult life. Though fertility of rats with U/L UDT was significantly less (p < 0.01) than the controls, no significant alterations were found in the levels of serum testosterone, FSH and LH. Even though variations in the hormone levels may be responsible, to a certain extent, for the decrease in fertility potential in U/L UDT, estimation of sex hormone levels in U/L UDT is not a sensitive indicator of fertility potential. U/L UDT may additionally be affecting fertility through non-endocrinological mechanisms.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Rats
/
Testosterone
/
Male
/
Luteinizing Hormone
/
Rats, Wistar
/
Cryptorchidism
/
Fertility
/
Follicle Stimulating Hormone
/
Animals
Type of study:
Prognostic study
Language:
English
Journal:
Indian J Pediatr
Year:
1999
Type:
Article
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