Steroid sensitive nephrotic syndrome.
Indian J Pediatr
;
2002 Dec; 69(12): 1059-63
Article
in English
| IMSEAR
| ID: sea-83686
ABSTRACT
Nephrotic syndrome in children is a common recurrent disease. Most of the cases are due to minimal change disease with a favourable outcome. More than 90% of children with minimal change disease respond to corticosteroid therapy (steroid sensitive nephrotic syndrome). 40-60% experience frequent relapses or have steroid dependence. These children require frequent corticosteroid therapy and/or immunomodulators or treatment with immunosuppressants, and are at high risk of cumulative steroid toxicity and side effects of cytotoxic therapy. Children with frequent relapses or steroid dependence should be managed in consultation with a pediatric nephrologist. Despite relapsing course, progression of minimal change nephrotic syndrome to end stage renal disease is extremely rare.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Recurrence
/
Biopsy
/
Humans
/
Child
/
Child, Preschool
/
Patient Education as Topic
/
Adrenal Cortex Hormones
/
Immunosuppressive Agents
/
Nephrotic Syndrome
Type of study:
Diagnostic study
Language:
English
Journal:
Indian J Pediatr
Year:
2002
Type:
Article
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