Translocation Down's syndrome.
Indian J Pediatr
;
1990 Mar-Apr; 57(2): 265-71
Article
in English
| IMSEAR
| ID: sea-83821
ABSTRACT
Among the 500 Down syndrome children karyotyped, 15 (3%) were due to translocation; 10 were 21;21 translocation and five 14;21. There were 9 cases of de novo translocations, while 6 were inherited from father or mother. Family history was characteristic in all the translocation cases, with younger parental age, fetal wastage in the family, recurrence and with the affected child often being either the first or the only liveborn in the family. The pattern of translocation in Madras and the significance of family history in genetic counselling are discussed.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Pedigree
/
Translocation, Genetic
/
Female
/
Humans
/
Male
/
Pregnancy
/
Maternal Age
/
Down Syndrome
/
India
/
Karyotyping
Country/Region as subject:
Asia
Language:
English
Journal:
Indian J Pediatr
Year:
1990
Type:
Article
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