Crossmatching considerations in renal transplantation.
Article
in English
| IMSEAR
| ID: sea-85286
ABSTRACT
During the year 1993-1994, 73 renal transplant cases have been screened for the presence of anti-HLA antibodies using the standard lymphocytotoxicity assay. Amongst the 9 related transplantations with 100% negative crossmatch 6 were successful. About 8.2% of the patients had a shift from positive to negative crossmatch. It was observed that an increased number of transfusions (ranging from 3 to 21) in males and females yielded negative crossmatches. In females, however, owing to various factors such as pregnancies, parity and infections, varied percentages were observed with different donors. The crossmatches in diabetics and hypertensive patients suggest no particular correlation and probably have no role in the outcome of the assay.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Blood Transfusion
/
Female
/
Humans
/
Male
/
Pregnancy
/
Cytotoxicity Tests, Immunologic
/
Histocompatibility Testing
/
Kidney Transplantation
/
Immunization
/
HLA Antigens
Language:
English
Year:
1996
Type:
Article
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