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Human leucocyte antigen and insulin dependent diabetes mellitus.
Article in English | IMSEAR | ID: sea-85752
ABSTRACT
HLA typing was done in 25 cases of insulin dependent diabetes mellitus (IDDM) and compared with 60 healthy controls. There was a significantly increased frequency of HLA B-8, HLA B-12 and HLA DR-3 in IDDMO. The odds ratio (relative risk) of developing IDDM for HLA B-8 was 4.42 (p less than 0.10), for HLA B-12 was 3.56 (p less than 0.10) and for HLA DR3 9.75 (p less than 0.001). There was no correlation of HLA specificity with complications of diabetes.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / HLA-B Antigens / Ethnicity / Case-Control Studies / HLA-B8 Antigen / HLA-DR3 Antigen / HLA-DR4 Antigen / Risk Factors / Adolescent / Adult Type of study: Etiology study / Observational study / Risk factors Country/Region as subject: Asia Language: English Year: 1991 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Humans / HLA-B Antigens / Ethnicity / Case-Control Studies / HLA-B8 Antigen / HLA-DR3 Antigen / HLA-DR4 Antigen / Risk Factors / Adolescent / Adult Type of study: Etiology study / Observational study / Risk factors Country/Region as subject: Asia Language: English Year: 1991 Type: Article