Primary IgA nephropathy in adults.
Article
in English
| IMSEAR
| ID: sea-87250
ABSTRACT
IgA nephropathy was found in 9.6% of 649 adults with primary glomerulonephritis. Hypertension was detected in 51.6% and renal failure in 32.3%. A nephrotic presentation was seen in 22.6% and recurrent macroscopic hematuria in 17.7%. On light microscopy, mesangial hypercellularity and an increase in mesangial matrix were frequently seen (74.2%). Immunofluorescence studies demonstrated IgA in all patients along with C3 in 61.3%, IgM in 27.4% and IgG in 11.3%. Followup was possible in 61.3% for mean period of 17.3 months. No clinical or biochemical abnormalities were detected on followup in 26.3%. Progression to end stage renal disease was noted in 7.9%.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Retrospective Studies
/
Follow-Up Studies
/
Adolescent
/
Adult
/
Glomerulonephritis, IGA
/
Kidney Failure, Chronic
/
Middle Aged
Type of study:
Observational study
/
Prognostic study
Language:
English
Year:
1993
Type:
Article
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