Role of selegiline as initial monotherapy in early Parkinson's disease.
Article
in English
| IMSEAR
| ID: sea-87644
ABSTRACT
Twenty patients of Idiopathic Prakinson's disease in the early phase were enrolled to study the efficacy and safety of selegiline as monotherapy. The mean duration of time before levodopa had to be initiated was 9.75 months. The UPDRS scores for activities of daily living, motor examination, tremor and total score showed significant improvement initially with subsequent worsening. Selegiline was well tolerated and there were no serious side-effects. In conclusion, selegiline may have a short lasting symptomatic effect in IPD and is well tolerated.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Parkinson Disease
/
Safety
/
Time Factors
/
Tremor
/
Female
/
Humans
/
Male
/
Activities of Daily Living
/
Selegiline
/
Levodopa
Type of study:
Observational study
/
Prognostic study
Language:
English
Year:
1994
Type:
Article
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