Treatment of acute infectious purpura fulminans with activated protein C.
Indian Pediatr
;
2006 Jun; 43(6): 535-8
Article
in English
| IMSEAR
| ID: sea-8826
ABSTRACT
Infectious purpura fulminans is associated with high mortality and morbidity despite standard antimicrobial therapy. We report satisfactory clinical outcome in two children with sepsis associated purpura fulminans who were treated with activated protein C (APC). There is need for proper evaluation of the efficacy of this extremely expensive therapeutic modality by randomized controlled trials before it is made standard of care in childhood infectious purpura fulminans.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
IgA Vasculitis
/
Humans
/
Male
/
Blood Coagulation Factors
/
Protein C
/
Child, Preschool
/
Acute Disease
/
Treatment Outcome
/
Receptors, Cell Surface
/
Infant
Type of study:
Controlled clinical trial
Language:
English
Journal:
Indian Pediatr
Year:
2006
Type:
Article
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