Safety and efficacy of liposomal amphotericin B in patients with cryptococcal meningitis.
Article
in English
| IMSEAR
| ID: sea-88354
ABSTRACT
Four patients with cryptococcal meningitis were successfully treated with liposomal amphotericin B prepared at our institute using Soya phosphatidylcholine and cholesterol. In one patient, response with 1 mg/kg/day treatment was poor. However, on increasing the dose to 2 mg/kg/day, a good response was observed with CSF becoming negative for Cryptococcus neoformans after seven days of this enhanced dose. L-AMP-LRC-1 was found to be well tolerated and a major advantage was observed in two renal transplant patients in whom it could be given safely.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Infusions, Intravenous
/
Female
/
Humans
/
Drug Carriers
/
Amphotericin B
/
Follow-Up Studies
/
Treatment Outcome
/
Meningitis, Cryptococcal
/
Clinical Trials, Phase II as Topic
/
Adult
Type of study:
Observational study
/
Prognostic study
Language:
English
Year:
2001
Type:
Article
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