Evolving trends in the etiopathogenesis of acute renal failure.
Article
in English
| IMSEAR
| ID: sea-88949
ABSTRACT
Research during the last few years has uncovered the mechanisms responsible for acute renal failure. During the initiation phase of acute tubular necrosis sublethal injury, apoptosis or necrosis of the tubular epithelium, hemodynamic alterations, tubule obstruction and back leakage occur. Hypofiltration persists due to imbalance between endothelins and endothelium derived nitric oxide, medullary congestion and tubuloglomerular feedback. Recovery is characterised by tubular epithelium regeneration. A greater understanding of the pathogenesis of acute renal failure will allow better management of such cases.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Renal Circulation
/
Uremia
/
Humans
/
Risk Factors
/
Apoptosis
/
Acute Kidney Injury
/
Glomerular Filtration Rate
/
Kidney Tubular Necrosis, Acute
Type of study:
Etiology study
/
Risk factors
Language:
English
Year:
2000
Type:
Article
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