IgA associated glomerulonephritis.
Article
in English
| IMSEAR
| ID: sea-90044
ABSTRACT
Immunohistological analysis of 1146 renal biopsies revealed IgA associated glomerulonephritis (IgAGN) in 83 (7.24%) patients (33 children, 50 adults). Clinical features were unusually severe in a high proportion. Nephrotic syndrome (NS) responding poorly to prednisolone was found in 24%, hypertension (HT) in 39%, and azotemia in 34% of patients. NS was slightly more frequent in children than in adults, but HT and azotemia occurred twice as often in adults as in children. Histologically, extensive glomerular crescents and sclerosis were prominent. In addition, moderate arteriolitis and arteriolosclerosis and marked tubulointerstitial nephropathy were notable features. Thus, a low incidence and marked severity characterized IgAGN in this study.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Proteinuria
/
Uremia
/
Humans
/
Child
/
Child, Preschool
/
Incidence
/
Adult
/
Glomerulonephritis, IGA
/
Hypertension
/
India
Type of study:
Incidence study
/
Prognostic study
Country/Region as subject:
Asia
Language:
English
Year:
1992
Type:
Article
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