A study of nerve conduction velocity in patients on diphenylhydantoin therapy.
Article
in English
| IMSEAR
| ID: sea-90220
ABSTRACT
Peripheral nerve conduction studies were performed in 30 epileptics, treated with DPH and results were compared with age and sex matched controls. There was significant reduction in the amplitude of sensory nerve action potential of median (26.65 +/- 14.71 mu v) and superficial radial nerve (25.65 +/- 10.08 mu v) (p < 0.001) in DPH treated group as compared to controls, (median nerve 42.64 +/- 15.93 uv and superficial radial nerve 40.72 +/- 24.74 mu v). The results suggest that DPH causes a subclinical distal axonal neuropathy in therapeutic dosage.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Phenytoin
/
Time Factors
/
Action Potentials
/
Humans
/
Peripheral Nervous System Diseases
/
Epilepsy
/
Motor Neurons
/
Neural Conduction
/
Neurons, Afferent
Language:
English
Year:
1992
Type:
Article
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