Mitral annular calcification in untreated chronic renal failure.
Article
in English
| IMSEAR
| ID: sea-90442
ABSTRACT
Clinical, biochemical, radiological and echo-cardiographic (echo) evaluation was done prospectively in 50 patients of untreated end stage chronic renal failure (CRF). While clinically congestive cardiac failure (CCF) was diagnosed in 24%, low ejection fraction on echo was found in only 16%. Echo in these cases showed evidence of cardiac chamber dilatation in most (mean LVID (D) 54.1 +/- 6.51 and (S) 36.4 +/- 6.9 mm, but parameters of cardiac functions were normal in most. Mitral annular calcification (MAC) was detected on echo in 26%. On comparing patients with MAC (Group I) and those without MAC (Group II), the aetiological factor found more frequently in Group I was diabetes (61.5% vs 35.1%, P less than 0.05). Clinical features such as older age (mean age 54 years vs 45.5 years), severe hypertension, and grade IV and above murmur (15.2% vs none) were more common among group I patients. However, the difference was not statistically significant. Parameters of calcium metabolism were similar in the two groups. Conduction disturbances (30.7% vs 5.4%) were significantly more common in Group I (P = 0.05). The mitral regurgitation due to MAC was of no haemodynamic significance. Complications of MAC syndrome were rare.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Chronic Kidney Disease-Mineral and Bone Disorder
/
Humans
/
Calcinosis
/
Echocardiography
/
Calcium
/
Prospective Studies
/
Adult
/
Electrocardiography
/
Hypertension
/
Kidney Failure, Chronic
Type of study:
Observational study
Language:
English
Year:
1992
Type:
Article
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