Incidence of intermediate syndrome in organophosphorous poisoning.
Article
in English
| IMSEAR
| ID: sea-90713
ABSTRACT
Seventy two patients admitted to the Intensive Care Unit following ingestion of organophosphorus compounds were studied prospectively with two different doses of pralidoxime (PAM). One group received 1 gm immediately after admission and no further PAM and the other group received infusion of PAM, 1 gm 8 hourly for four days (total 12 gms). The incidence of type II paralysis or intermediate syndrome was 47%. We observed a higher incidence in the 4 days of infusion of PAM group (61%) (20 patients) as compared to the single Bolus dose group (39%) (13 patients). Relative risk 1.48 (confidence interval = 0.9-2.4).
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Organophosphorus Compounds
/
Paralysis
/
Pralidoxime Compounds
/
Respiratory Paralysis
/
Syndrome
/
Infusions, Intravenous
/
Female
/
Humans
/
Male
/
Drug Administration Schedule
Type of study:
Controlled clinical trial
/
Etiology study
/
Incidence study
/
Observational study
/
Risk factors
Language:
English
Year:
1995
Type:
Article
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