Short term anti-tubercular drug therapy and hepatic microsomal enzyme activity. Antipyrine metabolism as an index.
Article
in English
| IMSEAR
| ID: sea-91112
ABSTRACT
The effect of short course chemotherapy on the drug metabolising capacity of the liver was studied in 7 newly diagnosed pulmonary tuberculosis patients, using antipyrine as a model drug. Antipyrine elimination half-life and plasma clearance rate were not significantly altered by 3 weeks of therapy. It is concluded that short course chemotherapy does not affect antipyrine metabolising enzyme activity.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Saliva
/
Time Factors
/
Tuberculosis, Pulmonary
/
Humans
/
Male
/
Microsomes, Liver
/
Antipyrine
/
Adult
/
Drug Evaluation
/
Antitubercular Agents
Type of study:
Prognostic study
Language:
English
Year:
1990
Type:
Article
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