Randomised double blind placebo controlled clinical trial of sucralfate and ranitidine in chronic duodenal ulcer.
Article
in English
| IMSEAR
| ID: sea-91195
ABSTRACT
A double blind, randomised, placebo controlled clinical trial was carried out in endoscopically proved chronic duodenal ulcer patients to compare the efficacy of sucralfate and ranitidine. Sucralfate 1 g four times daily and ranitidine 150 mg twice daily were found to be equally effective in inducing ulcer healing (73.1% and 82.1% respectively) during the 6-week treatment period. The rate of recurrence of the ulcer within six months after the initial treatment (84.2% and 82.6%) was also comparable in the sucralfate and ranitidine groups. Sucralfate and ranitidine are equally effective in ulcer healing and prevention of ulcer relapse.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ranitidine
/
Recurrence
/
Sucralfate
/
Humans
/
Randomized Controlled Trials as Topic
/
Double-Blind Method
/
Follow-Up Studies
/
Adult
/
Duodenal Ulcer
Type of study:
Controlled clinical trial
/
Observational study
/
Prognostic study
Language:
English
Year:
1990
Type:
Article
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