Nifedipine in migraine and tension headache: a randomised double blind crossover study.
Article
in English
| IMSEAR
| ID: sea-91279
ABSTRACT
Nifedipine was evaluated in the prophylaxis of 28 patients each of migraine and tension headache using a double blind cross over design with random allocation to drug or placebo group. The duration of the trial was 3 months with a 2 week run-in period and 2 week wash-oat period separating two treatment periods of 4 weeks each. A satisfactory response was obtained in 71.4% of migraineurs (p < 0.001) and 28.6% of patients with tension headache (p = N.S). Minor side effects were observed in 5 patients. Nifedipine is a useful agent for the management of migraine as it reduces frequency and severity of pain but the drug cannot be recommended for tension headache.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Time Factors
/
Female
/
Humans
/
Male
/
Drug Administration Schedule
/
Calcium Channel Blockers
/
Nifedipine
/
Double-Blind Method
/
Tension-Type Headache
/
Cross-Over Studies
Type of study:
Controlled clinical trial
Language:
English
Year:
1995
Type:
Article
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