Clinicopathological profile of subacute hepatic failure.
Article
in English
| IMSEAR
| ID: sea-91280
ABSTRACT
Twenty two patients of subacute hepatic failure (SAHF), diagnosed when jaundice progressed for more than 8 weeks with appearance of ascites, with or without encephalopathy, along with biochemical evidence of hepatocellular damage, were studied. The male and female ratio was 4.51 and majority (45.4%) of cases were between the age group of 41-50. The mean biochemical values were S.bilirubin; 9.2 +/- 3.8 mg/dl SGOT; 94.4 +/- 25.0 I.U./lit., SGPT; 107.8 +/- 32.7 I.U./lit., S.Protein; 5.2 +/- 3.5 secs. Ascitic fluid analysis showed transudate in 16 (72.7%) and exudate in 6 (27.2%) patients. Bacterial peritonitis was found in 5 (22.7%) patients. Liver biopsy showed bridging and submassive necrosis. The complications developed in the hospital were renal failure (36.3%), infection (27.2%), G.I. bleeding (18.1%) and encephalopathy (13.6%). The mortality was (86.3%). Out of 3 (13.6%) patients who survived, only two recovered completely and one had biochemical evidence of hepatocellular necrosis after 6 months of follow up.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Ascites
/
Biopsy
/
Female
/
Humans
/
Male
/
Hepatic Encephalopathy
/
Acute Disease
/
Survival Rate
/
Prospective Studies
/
Follow-Up Studies
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Language:
English
Year:
1996
Type:
Article
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