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Short course ciprofloxacin therapy for enteric fever.
Mathai, D; Kudva, G C; Keystone, J S; Kozarsky, P E; Jesudason, M V; Lalitha, M K; Kaur, A; Thomas, M; John, J; Pulimood, B M.
Article in English | IMSEAR | ID: sea-91418
ABSTRACT
A short course of ciprofloxacin, 750 mgm b.i.d. for 7 days was found to be effective in the treatment of enteric fever in 21 hospitalized patients with S.typhi (18) and S.paratyphi A(3). Median time for fever response was 3 days. All isolates were susceptible to ciprofloxacin (MIC 0.0078-0.062 mcgm/ml). The mean serum peak and trough levels were 5.4 and 1.6 mcgm/ml respectively. Stool cultures were free of Salmonellae on follow up (11-24 weeks). Two developed recurrence of paratyphoid fever, 17 days and 4 months after therapy.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Recurrence / Salmonella paratyphi A / Time Factors / Typhoid Fever / Female / Humans / Male / Drug Administration Schedule / Ciprofloxacin / Paratyphoid Fever Language: English Year: 1993 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Recurrence / Salmonella paratyphi A / Time Factors / Typhoid Fever / Female / Humans / Male / Drug Administration Schedule / Ciprofloxacin / Paratyphoid Fever Language: English Year: 1993 Type: Article